Science Archives - CarnoSyn https://www.carnosyn.com/category/science/ Build Better Muscle Wed, 24 Jul 2024 23:29:17 +0000 en-US hourly 1 https://wordpress.org/?v=6.8.3 https://www.carnosyn.com/wp-content/uploads/2022/03/cropped-favicon-32x32-1-32x32.png Science Archives - CarnoSyn https://www.carnosyn.com/category/science/ 32 32 Exploring Creatine Supplementation and the Complementary Role of CarnoSyn® Beta-Alanine in Supporting the Function of the Creatine Kinase-Phosphocreatine System https://www.carnosyn.com/exploring-creatine-supplementation-and-the-complementary-role-of-carnosyn-beta-alanine/ https://www.carnosyn.com/exploring-creatine-supplementation-and-the-complementary-role-of-carnosyn-beta-alanine/#respond Wed, 24 Jul 2024 22:49:03 +0000 https://www.carnosyn.com/?p=9635 Research has shown that the synergy between creatine and CarnoSyn® beta-alanine amplifies their individual effects, offering a comprehensive solution for enhancing athletic performance. CarnoSyn® beta-alanine addresses the fatigue associated with high-intensity workouts, allowing individuals to push through more repetitions, while creatine provides the energy substrate needed for these extended efforts. Clinical tests show significant increases […]

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]]> Research has shown that the synergy between creatine and CarnoSyn® beta-alanine amplifies their individual effects, offering a comprehensive solution for enhancing athletic performance. CarnoSyn® beta-alanine addresses the fatigue associated with high-intensity workouts, allowing individuals to push through more repetitions, while creatine provides the energy substrate needed for these extended efforts. Clinical tests show significant increases in strength and stamina when stacking these two powerhouse ingredients.1

CarnoSyn® beta-alanine plays a significant role in enhancing the effectiveness of creatine supplementation, particularly in scenarios where maintaining optimal muscle function and delaying fatigue are crucial. CarnoSyn® supplementation increases the levels of muscle carnosine, which serves as a buffer against acidification during intense exercise. This buffering capacity helps to slow the decline in intramuscular pH that occurs with sustained muscle contraction. By mitigating the decrease in pH, CarnoSyn® supplementation supports the function of the creatine kinase-phosphocreatine (CK-PCr) system.

The CK-PCr system relies on an optimal pH environment for its efficiency in regenerating ATP from ADP. When pH levels drop due to acidification during exercise, the efficiency of the CK-PCr system decreases, leading to reduced muscle power output and eventual fatigue. However, CarnoSyn® beta-alanine supplementation can help maintain a more favorable pH environment, thereby enhancing the ability of the CK-PCr system to regenerate ATP. Therefore, in conjunction with creatine supplementation, CarnoSyn® plays a complementary role in optimizing muscle energy metabolism. By increasing buffering capacity and delaying the onset of fatigue, CarnoSyn® supports the function of the CK-PCr system, leading to improved athletic performance during high-intensity and short-duration activities.

Creatine is a naturally occurring compound found in the body, primarily in the muscles, where it plays a crucial role in energy metabolism. Creatine is involved in the rapid production of ATP (adenosine triphosphate), which is the primary energy currency of cells. When muscles contract, they use ATP for energy, and this ATP is rapidly depleted during intense exercise. Creatine kinase (CK) is an enzyme found in muscles and other tissues that catalyzes the transfer of a phosphate group from phosphocreatine (PCr) to ADP (adenosine diphosphate), forming ATP. This reaction is reversible and occurs rapidly, allowing the regeneration of ATP from ADP, which is essential for maintaining energy levels during high-intensity exercise.

The CK-PCr system refers to the coupled reactions involving creatine kinase and phosphocreatine. Phosphocreatine serves as a readily available high-energy phosphate reservoir that can quickly regenerate ATP from ADP, providing a rapid and immediate source of energy during muscle contraction. However, the efficiency of the CK-PCr system can be compromised under certain conditions, such as decreases in pH (acidification) that occur during intense exercise. This decrease in pH can impair the ability of creatine kinase to regenerate ATP from ADP, leading to a
decrease in muscle power output and eventual fatigue. Supplementation with creatine can increase the levels of phosphocreatine in muscles, thereby enhancing the capacity of the CK-PCr system to regenerate ATP during exercise. Supplementation of creatine and CarnoSyn® beta-alanine has been shown to improve strength, power, and muscle endurance, particularly during high-intensity and short-duration activities.

Overall, creatine and the CK-PCr system play crucial roles in muscle energy metabolism, helping to sustain ATP levels and power output during exercise, and supplementation with CarnoSyn® and creatine can enhance these processes, leading to improved athletic performance. In addition to physical performance benefits, research has shown that CarnoSyn® and creatine contribute to improved cognitive function. By integrating CarnoSyn® and creatine into your formulations, you are providing high-quality supplements and a premium consumer experience with the combined benefits of both cognitive and physical performance.

To learn more, visit: https://www.carnosyn.com/carnosyn-creatine/

1 Hoffman, J et al., 2006. Effect of creatine and beta-alanine supplementation on performance and endocrine responses in strength/power athletes. Int J Sport Nutr and Exercise Metabolism, 16: 430−446.

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]]> https://www.carnosyn.com/exploring-creatine-supplementation-and-the-complementary-role-of-carnosyn-beta-alanine/feed/ 0 What Are the Side Effects of Taking Beta-Alanine? https://www.carnosyn.com/beta-alanine-side-effects/ https://www.carnosyn.com/beta-alanine-side-effects/#respond Wed, 04 Oct 2023 16:46:53 +0000 https://www.carnosyn.com/?p=5480 Most athletes are familiar with the many benefits of beta-alanine. Many rely on beta-alanine supplementation for increased endurance, faster muscle growth and recovery, and laser focus. The benefits can dramatically enhance workouts and lead to bigger gains and PRs. But what are the side-effects of beta-alanine? Here’s what you need to know about beta-alanine supplementation […]

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]]> Most athletes are familiar with the many benefits of beta-alanine. Many rely on beta-alanine supplementation for increased endurance, faster muscle growth and recovery, and laser focus. The benefits can dramatically enhance workouts and lead to bigger gains and PRs. But what are the side-effects of beta-alanine? Here’s what you need to know about beta-alanine supplementation and how to minimize the side effects while maximizing your results.

What is Beta-Alanine?

First, what is beta-alanine exactly? Beta-alanine is a non-proteogenic amino acid that’s naturally produced in the body and also found in foods such as certain meat and fish. It combines with the amino acid histidine to form a dipeptide called carnosine. Over time, carnosine buffers the pH decline that causes the onset of muscle fatigue and failure, while building endurance and improving recovery. The body’s natural production and most diets, however, do not have enough beta-alanine needed to improve athletic performance.

According to The International Society of Sports Nutrition (ISSN), supplementing with beta-alanine for a minimum of two to four weeks can “improve exercise performance, with more pronounced effects” and “currently appears to be safe in healthy populations at recommended doses”[1].

What to Expect When Ingesting Beta-Alanine

supplementing with beta-alanine

Ingesting high amounts of beta-alanine activates certain neurons responsible for initiating the temporary itching and tingling of the skin, typically on the neck, shoulders, and/or arms. This sensation is referred to as paresthesia.

While paresthesia can be slightly uncomfortable, there is no need to be alarmed. According to one study, there are no harmful effects associated with paresthesia that occurs after ingesting beta-alanine.* And the International Society of Sport Nutrition has concluded that “beta-alanine supplementation currently appears to be safe in healthy populations at recommended doses.”

Keep in mind that each person’s paresthesia threshold varies, however, so the level of itching and/or tingling may also vary depending upon the individual, the dosage amount, and food intake prior to supplementing with beta-alanine.

Minimizing the Side Effects

To minimize the side effects of beta-alanine, stack multiple doses throughout the day or use a sustained release version. SR CarnoSyn®’s sustained release formulation is designed to minimize paresthesia sensations associated with instant-release beta-alanine. This delivery system allows athletes to ingest higher levels of beta-alanine comfortably and with extended absorption, which converts to faster increases in muscle carnosine (and faster gains). Keep in mind that sufficient daily dosage is key for performance improvement.

How Safe Are the Ingredients in Your Pre-Workout?

While beta-alanine is typically regarded as safe, it’s important to know what insidious ingredients might be hiding in your pre-workout supplements — especially when generic brands abound.

SR CarnoSyn® is a patented ingredient available in tablet form. It contains the only beta-alanine that has successfully obtained NDI status from the FDA. CarnoSyn® beta-alanine can be used in a number of dosage forms: powders, tablets, capsules, stick packets, chewables/lozenges, and more.

CarnoSyn® vs. Generic Beta-Alanine

Not all beta-alanine is created equal. It is important to know the difference between generic beta-alanine and a quality supplement you can trust. In terms of CarnoSyn® vs. generic beta-alanine, there is a significant difference. Generic beta-alanine is not backed by science, nor protected by trademark registration. The quality of generic beta-alanine cannot be trusted to match that of patented CarnoSyn® beta-alanine. Manufacturers often claim their products have the same chemical structure identification, purity levels, and even the same benefits. Those claims, however, are not backed by the FDA for their process and purity, nor supported by science.

CarnoSyn® is scientifically proven to be effective at improving athletic performance in all types of athletes. In fact, CarnoSyn®‘s performance-boosting benefits are backed by more than 55 studies. These studies helped secure 16 global patents. The patented use of CarnoSyn® beta-alanine has led to significant advancements in muscle performance technology. CarnoSyn® is the only beta-alanine that has been certified by national and international agencies to be safe and effective, and the only beta-alanine to obtain the FDA status of New Dietary Ingredient (NDI) and Generally Recognized as Safe (GRAS) status. Containing ZERO banned substances, you’ll always know where your beta-alanine comes from—and that it’s safe and effective.

Instant Release vs. Sustained Release

There are two ways to get results with CarnoSyn® beta-alanine: via instant release and sustained release formulas. SR CarnoSyn® offers the same benefits as instant release CarnoSyn®, but in an advanced delivery system allowing higher dosing levels. Sustained-release properties also help minimize paresthesia and extend retention. Using instant release and sustained release in tandem gives athletes the ability to stack their dosing for higher quantities of beta-alanine and greater performance gains. For example, in a study comparing sustained-release and instant-release, SR CarnoSyn® demonstrated a 16.4% greater increase in muscle carnosine than instant beta-alanine.[2]

CarnoSyn® beta-alanine can be used in a number of dosage forms: powders, tablets, capsules, stick packets, chewables/lozenges, and more. SR CarnoSyn® is a patented ingredient available in tablet form. It contains the only beta-alanine that has successfully obtained FDA NDI status.

How Do I Find CarnoSyn®-Verified Brand Partners?

When you see brands with the CarnoSyn® logo, you’ll know you’ve found a product that contains the only proven and trusted beta-alanine ingredient. Visit the CarnoSyn® Verified page, where you can browse the list of CarnoSyn®-Verified Brand Partners and find beta-alanine products that provide the optimal dose at the best time.

TWO WAYS TO GET RESULTS

CarnoSyn® beta-alanine is available in two different forms—instant release and sustained release—offering two ways to dose. SR CarnoSyn® offers the same benefits as instant release CarnoSyn®, but in an advanced delivery system that allows for increased dosing for better results. When used in tandem, the combination of instant release and sustained release gives athletes the ability to stack their dosing for higher quantities of beta-alanine and even more performance gains.

CarnoSyn beta alanine

Instant Release

Learn more

Sustained release CarnoSyn beta alanine

Sustained Release

Learn more

 

CONTACT CARNOSYN® FOR MORE INFORMATION

 

Contact

[1] https://jissn.biomedcentral.com/articles/10.1186/s12970-015-0090-y

[2] https://link.springer.com/article/10.1007/s00726-018-2609-4

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]]> https://www.carnosyn.com/beta-alanine-side-effects/feed/ 0 Is Supplementing with CarnoSyn Beta-Alanine® Better Than Taking Carnosine Directly? https://www.carnosyn.com/is-supplementing-with-beta-alanine-better-than-taking-carnosine-directly/ https://www.carnosyn.com/is-supplementing-with-beta-alanine-better-than-taking-carnosine-directly/#respond Thu, 07 Sep 2023 00:10:19 +0000 https://www.carnosyn.com/?p=8497 What is Beta-Alanine? Beta-alanine is a non-proteogenic amino acid that’s naturally produced in the body and also found in foods such as certain meat and fish. It combines with the amino acid histidine to form a dipeptide called carnosine. Over time, carnosine acts as a buffer to help delay the onset of lactic acid and […]

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]]> What is Beta-Alanine?

Beta-alanine is a non-proteogenic amino acid that’s naturally produced in the body and also found in foods such as certain meat and fish. It combines with the amino acid histidine to form a dipeptide called carnosine. Over time, carnosine acts as a buffer to help delay the onset of lactic acid and muscle fatigue and failure, while building endurance and improving recovery. The body’s natural production and most diets, however, do not have enough beta-alanine needed to improve athletic performance.

What is Carnosine? 

Carnosine, also known as L-carnosine, is a naturally occurring substance found in the body. It’s most commonly known as a powerful antioxidant. This dipeptide or compound is made up of two amino acids–beta-alanine and histidine– that have linked. Carnosine can be found in the tissues of the body including the heart and the brain.

Carnosine’s Impact on Elite Athletes

Carnosine is instrumental in the improvement of muscle strength and performance during exercise. In 1938, scientists discovered carnosine as an important intracellular pH buffer in the muscle. During exercise, highly reactive hydrogen ions cause a fall in pH in the muscles, a process also referred to as acidification. Carnosine was found to have a perfect pKa value with the best buffering capacity for our ideal physiological condition. This discovery led to the study of carnosine’s impact on elite athletes and the benefits of raising carnosine levels for greater performance. High concentrations of carnosine reduce the level of acidity in the muscles. By safeguarding against lactic acid buildup, carnosine improves muscle elasticity and delays or prevents muscle fatigue.

Why Not Supplement with Carnosine Itself?

From building better muscle quality to increasing endurance and exercise performance, the effects of carnosine are significant and wide-reaching. But supplementing with carnosine is not the best way to increase carnosine levels in the body. Here are three reasons why not supplement with carnosine itself:

  1. Cost. Supplementing with carnosine directly can cost up to 25x more than beta-alanine.
  2. Efficiency. Even though it seems more efficient to elevate your body’s carnosine levels by taking carnosine directly, the opposite is actually true. During digestion, the body naturally breaks carnosine down into beta-alanine and histidine before turning it back into carnosine.
  3. Added Ingredients. It is common for “carnosine” products to contain only 40% beta-alanine. The rest is unneeded histidine and added ingredients.

Achieving Optimal Carnosine Levels

Beta-alanine is often referred to as the precursor for achieving optimal carnosine levels. This non-proteinogenic amino acid is responsible for how much carnosine is synthesized in the body. Research has shown that enough histidine is naturally present in the body to meet the demands of muscles for the synthesis of carnosine and that the limiting factor is beta-alanine. Beta-alanine supplementation augments the small amounts available from synthesis in the liver and from the ingestion of meat and fish. Supplemental beta-alanine combines with naturally occurring histidine to increase the levels of carnosine. Supplementing with the right dosage of beta-alanine is critical for achieving optimal levels of carnosine. The threshold for reaping the benefits of beta-alanine is 3.2 grams daily over 28 days. For athletes seeking to increase their performance, an average of 6.4 grams is recommended per day.

CarnoSyn® vs. Generic Beta-Alanine

Not all beta-alanine is created equal. It is important to know the difference between generic beta-alanine and a quality supplement you can trust. In terms of CarnoSyn® vs. generic beta-alanine, there is a significant difference. Generic beta-alanine is not backed by science, nor protected by trademark registration. The quality of generic beta-alanine cannot be trusted to match that of patented CarnoSyn® beta-alanine. Manufacturers often claim their products have the same chemical structure identification, purity levels, and even the same benefits. Those claims, however, are not backed by the FDA for their process and purity, nor supported by science.

CarnoSyn® is scientifically proven to be effective at improving athletic performance in all types of athletes. In fact, CarnoSyn®‘s performance-boosting benefits are backed by more than 55 studies. These studies helped secure 16 global patents. The patented use of CarnoSyn® beta-alanine has led to significant advancements in muscle performance technology. CarnoSyn® is the only beta-alanine that has been certified by national and international agencies to be safe and effective, and the only beta-alanine to obtain the FDA status of New Dietary Ingredient (NDI) and Generally Recognized as Safe (GRAS) status. Containing ZERO banned substances, you’ll always know where your beta-alanine comes from—and that it’s safe and effective.

Supplementing with CarnoSyn® is the best way to experience the benefits of elevated carnosine levels. When you see brands with the CarnoSyn® logo, you’ll know you’ve found a product that contains the only proven and trusted beta-alanine. Visit the CarnoSyn® Verified page, where you can browse the list of CarnoSyn®-Verified Brand Partners and find beta-alanine products that provide the optimal dose.

The post Is Supplementing with CarnoSyn Beta-Alanine® Better Than Taking Carnosine Directly? appeared first on CarnoSyn.

]]> https://www.carnosyn.com/is-supplementing-with-beta-alanine-better-than-taking-carnosine-directly/feed/ 0 Beta-Alanine — What’s the Proper Dosage? https://www.carnosyn.com/beta-alanine-proper-dosage/ https://www.carnosyn.com/beta-alanine-proper-dosage/#comments Thu, 10 Aug 2023 01:07:15 +0000 https://www.carnosyn.com/?p=5485 Ask any professional athlete, and they’ll tell you proper dosing is critical to the efficacy of a pre-workout supplement — and to your overall physical performance. Proper dosing also helps prevent paresthesia, an uncomfortable but harmless itching and tingling of the skin that’s common after taking high quantities of beta-alanine. (This reaction may vary depending […]

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]]> Ask any professional athlete, and they’ll tell you proper dosing is critical to the efficacy of a pre-workout supplement — and to your overall physical performance.

Proper dosing also helps prevent paresthesia, an uncomfortable but harmless itching and tingling of the skin that’s common after taking high quantities of beta-alanine. (This reaction may vary depending upon the individual, the dosage amount, and food intake prior to supplementing.)

Proper Dosing (and Stacking) of Beta-Alanine

How CarnoSyn and SR CarnoSyn work illustration
How CarnoSyn and SR CarnoSyn work

First, you should opt for a supplement that contains a fully tested, branded ingredient, such as CarnoSyn®, as opposed to generic beta-alanine. The fact is, with generic beta-alanine, there’s no real way of knowing if it is safe and effective–or that you’re getting the proper dose. Only CarnoSyn® is proven to improve athletic performance. In a 10-week study on high-intensity cyclists, supplementation with CarnoSyn® led to an overall 80% muscle carnosine increase. This was after an initial 58.8% increase at 4 weeks, followed by improved capacity and increased muscle carnosine thereafter.[1]

When it comes to proper dosing, a minimum of 90 grams over a period of 28 days is ideal. To amplify muscle performance, 179 grams over a 28-day period is recommended. These dosing regimens range on average from 3.2 to 6.4 grams per day. The higher the dose, the higher the carnosine retention, resulting in enhanced peak performance.

For athletes who choose to take the maximum dose, it doesn’t have to be taken all at once. Many athletes do what’s called stacking. This can be done via a pre-workout or post-workout, a standalone product in a single dose or multiple doses, or as a combination of pre/post formulations and standalone products.

What is a Loading Period?

Many athletes choose to obtain optimum beta-alanine intake by employing a “loading” phase or loading period into their workout regimen. A loading period is required to experience the benefits of supplementation. According to The International Society of Sports Nutrition (ISSN), supplementing with beta-alanine for a minimum of two to four weeks can “improve exercise performance, with more pronounced effects in open end-point tasks/time trials lasting one to four minutes in duration.”[2]

After the loading period, it’s important to take beta-alanine daily to achieve proven results–not just on workout days. Some athletes choose to reduce their beta-alanine intake at that point and enter into what’s referred to as a “maintenance” phase. Other athletes prefer to vary their dosage amount based on their daily activity–taking higher doses on training days, for example.

Instant Release vs. Sustained Release

There are two ways to get results with CarnoSyn® beta-alanine: via instant release and sustained release formulas. SR CarnoSyn® offers the same benefits as instant release CarnoSyn®, but in an advanced delivery system allowing higher dosing levels. Sustained-release properties also help minimize paresthesia and extend retention. Using instant release and sustained release in tandem gives athletes the ability to stack their dosing for higher quantities of beta-alanine and greater performance gains. For example, in a study comparing sustained-release and instant-release, SR CarnoSyn® demonstrated a 16.4% greater increase in muscle carnosine than instant beta-alanine.[3]

CarnoSyn® beta-alanine can be used in a number of dosage forms: powders, tablets, capsules, stick packets, chewables/lozenges, and more. SR CarnoSyn® is a patented ingredient available in tablet form. It contains the only beta-alanine that has successfully obtained FDA NDI status.

 

How Do I Find CarnoSyn®-Verified Brand Partners?

When you see brands with the CarnoSyn® logo, you’ll know you’ve found a product that contains the only proven and trusted beta-alanine ingredient. Visit the CarnoSyn® Verified page, where you can browse the list of CarnoSyn®-Verified Brand Partners and find beta-alanine products that provide the optimal dose at the best time.

 

TWO WAYS TO GET RESULTS

CarnoSyn® beta-alanine is available in two different forms—instant release and sustained release—offering two ways to dose. SR CarnoSyn® offers the same benefits as instant release CarnoSyn®, but in an advanced delivery system that allows for increased dosing for better results. When used in tandem, the combination of instant release and sustained release gives athletes the ability to stack their dosing for higher quantities of beta-alanine and even more performance gains.

CarnoSyn beta alanine

Instant Release

Learn more

Sustained release CarnoSyn beta alanine

Sustained Release

Learn more

 

CONTACT CARNOSYN® FOR MORE INFORMATION

 

Contact

[1] https://pubmed.ncbi.nlm.nih.gov/16868650/
[2] https://jissn.biomedcentral.com/articles/10.1186/s12970-015-0090-y
[3] https://link.springer.com/article/10.1007/s00726-018-2609-4

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]]> https://www.carnosyn.com/beta-alanine-proper-dosage/feed/ 10 Researchers Behind Recent Publication on SR CarnoSyn® Beta-Alanine Tablet’s Ability to Improve Cognitive Health Presenting at American College of Sports Medicine and Exercise Science (ACSM) 2023 Annual Meeting https://www.carnosyn.com/researchers-behind-recent-publication-on-sr-carnosyn-beta-alanine-tablets-ability-to-improve-cognitive-health-presenting-at-american-college-of-sports-medicine-and-exercise-science-acs/ https://www.carnosyn.com/researchers-behind-recent-publication-on-sr-carnosyn-beta-alanine-tablets-ability-to-improve-cognitive-health-presenting-at-american-college-of-sports-medicine-and-exercise-science-acs/#respond Wed, 17 May 2023 17:50:01 +0000 https://www.carnosyn.com/?p=7630 CARLSBAD, CA, MAY 17, 2023—CarnoSyn® Brands and parent company Natural Alternatives International, Inc. (“NAI”) (Nasdaq: NAII), are proud to sponsor Dr. Guilherme G. Artioli and announce that several other leading CarnoSyn® beta-alanine researchers will be presenting at the American College of Sports Medicine and Exercise Science (ACSM) Annual Meeting and World Congresses Conference in Denver, […]

The post Researchers Behind Recent Publication on SR CarnoSyn® Beta-Alanine Tablet’s Ability to Improve Cognitive Health Presenting at American College of Sports Medicine and Exercise Science (ACSM) 2023 Annual Meeting appeared first on CarnoSyn.

]]> CARLSBAD, CA, MAY 17, 2023—CarnoSyn® Brands and parent company Natural Alternatives International, Inc. (“NAI”) (Nasdaq: NAII), are proud to sponsor Dr. Guilherme G. Artioli and announce that several other leading CarnoSyn® beta-alanine researchers will be presenting at the American College of Sports Medicine and Exercise Science (ACSM) Annual Meeting and World Congresses Conference in Denver, CO on May 30-June 2, 2023.

Dr. Guilherme G. Artioli, of Manchester Metropolitan University, is a senior researcher and lecturer in physiology. Dr. Artioli has conducted and published 8 clinical studies around SR CarnoSyn® beta-alanine and carnosine health benefits. His beta-alanine supplementation research highlights include the positive impacts on cardio health, long term safety, and other health benefits beyond exercise physiology.

Dr. Artioli will be joined by other prominent CarnoSyn® research scientists, Drs. Jay Hoffman and Bryan Saunders, presenting at the same symposium, Build Your Base: New Developments on the Use of Buffering Ergogenic Aids, on Thursday, June 1 at 1:30 p.m. In addition, Drs. Jay Hoffman and Ishay Ostfeld will be presenting a thematic research poster, the Role of β-Alanine Ingestion on Cognitive Function, Mood, and Physical Function in Older Adults, on Thursday June 1 at 3:45 p.m. The research poster is based on a clinical study published on February 23, 2023 (Nutrients), which provided the biggest scale of participants with precise experimental designs and showed SR CarnoSyn® beta-alanine supplementation benefited cognitive function in sedentary older adults. This clinical study was the first conducted with SR CarnoSyn® beta-alanine 600 milligram tablets, providing 2.4 grams of daily supplementation. The study results indicated improved cognitive function in older adults whose cognitive function at baseline was at or below normal. In addition, results indicated significant depression score reductions using the Geriatric Depression Scale (GDS).

“CarnoSyn® Brands and NAI are especially proud to be sponsoring Dr. Artioli as he shares his expertise and discoveries at the ACSM symposium,” said Aaron Starr, Vice President, CarnoSyn® Brands. “As a science-based company, CarnoSyn® Brands has built a firm network with the top academic researchers across the globe—including Drs. Hoffman, Saunders, and Ostfeld. CarnoSyn® Brands goes to great lengths to not only verify our product claims via research, but to also sponsor ongoing exploration and examination to better understand the mechanisms behind the functions and benefits for the end user.”

About CarnoSyn® Brands:
CarnoSyn® Brands feature two clinically studied, patented ingredients available exclusively from Natural Alternatives International, Inc.: CarnoSyn® instant release beta-alanine powder and SR CarnoSyn® sustained release beta-alanine tablets. In 2019, CarnoSyn® beta-alanine successfully obtained NDI status from the FDA and received Self-Affirmed GRAS (Generally Recognized as Safe) status. SR CarnoSyn®, an advanced delivery form of CarnoSyn®, received GRAS affirmation in 2017. The GRAS affirmation allows NAI to broaden their product offerings within the food and beverage industries, including medical and other fortified food products. For more information about CarnoSyn® in sports nutrition, please visit: www.carnosyn.com. For information on SR CarnoSyn® in healthy aging and wellness, visit srcarnosyn.com.

About NAI:
NAI, headquartered in Carlsbad, California, is a leading formulator, manufacturer and marketer of nutritional supplements and provides strategic partnering services to its customers. NAI’s comprehensive partnership approach offers a wide range of innovative nutritional products and services to clients including scientific research, proprietary ingredients, customer-specific nutritional product formulation, product testing and evaluation, marketing management and support, packaging and delivery system design, regulatory review, and international product registration assistance. For more information about NAI, please visit www.nai-online.com.

Contact:
Renee Michaelson
Director of Global Marketing
NAI/CarnoSyn® Brands
(760) 736-7700
info@nai-online.com

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]]> https://www.carnosyn.com/researchers-behind-recent-publication-on-sr-carnosyn-beta-alanine-tablets-ability-to-improve-cognitive-health-presenting-at-american-college-of-sports-medicine-and-exercise-science-acs/feed/ 0 Newly Published Study Shows SR CarnoSyn® Beta-Alanine Improves Cognitive Function In Older Adults https://www.carnosyn.com/newly-published-study-shows-sr-carnosyn-beta-alanine-improves-cognitive-function-in-older-adults/ https://www.carnosyn.com/newly-published-study-shows-sr-carnosyn-beta-alanine-improves-cognitive-function-in-older-adults/#respond Thu, 23 Feb 2023 16:07:43 +0000 https://www.carnosyn.com/?p=7562 CARLSBAD, CA, February 23, 2023—Natural Alternatives International, Inc. (“NAI”) (Nasdaq: NAII), an international leader in custom contract nutritional supplement manufacturing for over four decades, today announced that new research on the cognitive benefits of SR CarnoSyn® beta-alanine tablets, a patented sustained release delivery system owned by NAI, has been published in Nutrients. The benefits of […]

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]]> CARLSBAD, CA, February 23, 2023—Natural Alternatives International, Inc. (“NAI”) (Nasdaq: NAII), an international leader in custom contract nutritional supplement manufacturing for over four decades, today announced that new research on the cognitive benefits of SR CarnoSyn® beta-alanine tablets, a patented sustained release delivery system owned by NAI, has been published in Nutrients.

The benefits of CarnoSyn® Brands’ beta-alanine supplementation on functional performance in older adults has been reported in several prior clinical studies. These human studies have demonstrated that supplementing with CarnoSyn® beta-alanine can delay fatigue, increase strength, and improve functional performance. Various clinical studies concluded that CarnoSyn® beta-alanine supplementation is associated with improved executive function and that the anti-inflammatory and antioxidant effects of increased tissue carnosine levels supports improved health in older adults.

This new clinical study provided the biggest scale of participants with precise experimental designs, showing SR CarnoSyn® beta-alanine supplementation benefits cognitive function in sedentary older adults. This clinical study is also the first conducted with a 600 milligram SR CarnoSyn® beta-alanine tablet providing 2.4 grams of daily supplementation. The study results indicated improved cognitive function in older adults whose cognitive function at baseline was at or below normal. In addition, results indicated significant depression score reductions using the Geriatric Depression Scale (GDS).

The study included one hundred older adults between the ages of 60-80 who volunteered to participate in this double-blind, randomized controlled study. Any participant who had underlying neurological conditions was not eligible to enroll in the study. All interviews were conducted by a licensed physician. Participants were not permitted to use any additional nutritional supplements for at least six weeks prior to the study.

Before taking their first supplement, participants completed several tests consisting of written questionnaires to assess cognitive function and mood, and a computer-based exam to measure cognitive and executive function. In addition, a series of physical function tests were performed.

Testing occurred prior to supplementation, at the midpoint, and at week ten. Participants were instructed to consume two 600 mg tablets twice per day for the duration of the ten-week study. The SR CarnoSyn® beta-alanine supplement and the placebo were identical in appearance.

Cognitive and mood measures consisted of cognitive function assessments, including the Montreal Cognitive Assessment (MoCA), the Stroop pattern recognition test, and the Profile of Mood States (POMS). In addition, participants were also asked to complete the Geriatric Depression Scale (GDS) and the Geriatric Anxiety Scale (GAS).

SR CarnoSyn® has six research studies showing brain health and mood improvement, with numerous benefits for users:

  • Improves executive functioning, mental clarity and enhances cognitive process.
  • Reduces mental fatigue.
  • Supports brain health, cognitive function, and memory.
  • Studies show improved attention and task focus in adults.
  • Helps boost mental clarity, concentration, and alertness.
  • Promotes a healthy response to everyday stress.
  • Fosters a more balanced mood and supports a sense of calm.

About CarnoSyn® Brands:
CarnoSyn® Brands feature two clinically studied, patented ingredients available exclusively from Natural Alternatives International, Inc.: CarnoSyn® instant release beta-alanine powder and SR CarnoSyn® sustained release beta-alanine tablets. In 2019, CarnoSyn® beta-alanine successfully obtained NDI status from the FDA and received Self-Affirmed GRAS (Generally Recognized as Safe) status. SR CarnoSyn®, an advanced delivery form of CarnoSyn®, received GRAS affirmation in 2017. The GRAS affirmation allows NAI to broaden their product offerings within the food and beverage industries, including medical and other fortified food products.

About NAI:
NAI, headquartered in Carlsbad, California, is a leading formulator, manufacturer and marketer of nutritional supplements and provides strategic partnering services to its customers. NAI’s comprehensive partnership approach offers a wide range of innovative nutritional products and services to clients including scientific research, proprietary ingredients, customer-specific nutritional product formulation, product testing and evaluation, marketing management and support, packaging and delivery system design, regulatory review, and international product registration assistance. For more information about NAI, please visit www.nai-online.com.

For more information, visit: www.srcarnosyn.com

Contact:

Renee Michaelson
Director of Global Marketing
NAI/CarnoSyn® Brands
(760) 736-7700
info@nai-online.com 

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]]> https://www.carnosyn.com/newly-published-study-shows-sr-carnosyn-beta-alanine-improves-cognitive-function-in-older-adults/feed/ 0 Is Beta-Alanine an Amino Acid Supplement? https://www.carnosyn.com/is-beta-alanine-an-amino-acid-supplement/ https://www.carnosyn.com/is-beta-alanine-an-amino-acid-supplement/#respond Thu, 16 Feb 2023 23:31:34 +0000 https://www.carnosyn.com/?p=7542   For individuals wanting to improve their overall health and fitness, amino acids are a great place to start. These organic compounds are critical for supporting the body’s basic functions and serve as the building blocks of protein and muscle tissue. Amino acids have been compared to letters of the alphabet that, when joined together, […]

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For individuals wanting to improve their overall health and fitness, amino acids are a great place to start. These organic compounds are critical for supporting the body’s basic functions and serve as the building blocks of protein and muscle tissue. Amino acids have been compared to letters of the alphabet that, when joined together, form a complex language of protein chains within the body.

Due to their role in major physiological processes related to muscle building and fat loss, amino acids like beta-alanine are becoming increasingly well-known among athletes wishing to enhance their exercise and sports performance. So, what are the different kinds of amino acids and what impact do they have on the body? How can you make sure you’re getting enough amino acids? Are amino acids like beta-alanine safe to take in supplement form?

Essential Vs. Non-Essential Amino Acids

Just as humans must have water and oxygen to survive, our bodies need amino acids to function properly. There are hundreds of amino acids in nature, but the most important are the 20 that are genetically encoded (also referred to as “proteinogenic” amino acids). Nutritionists categorize these 20 amino acids into two groups: essential and non-essential.

The nine essential amino acids are also known as indispensable amino acids. They include histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine. These must be derived from our diet because they cannot be made by the body. (Humans lack the metabolic pathways required to synthesize them.) Essential amino acids are found in foods like beef, eggs, and dairy products.

Non-essential amino acids include alanine, arginine, asparagine, aspartic acid, cysteine, glutamic acid, glutamine, glycine, proline, serine, and tyrosine. These have historically been dubbed “non-essential” because the body is able to synthesize them from other amino acids, so they weren’t believed to be essential to our diets. However, so-called “non-essential” amino acids are quite essential to our health, so this century-old misnomer has limitations. According to one study, “Emerging evidence indicates dietary essentiality of ‘nutritionally non-essential amino acids’ for animals and humans to achieve their full genetic potential for growth, development, reproduction, lactation, and resistance to metabolic and infectious diseases.”

The other group, non-proteinogenic amino acids — like beta-alanine and creatine — are also called (and classified as) non-essential amino acids because the body has a pathway to produce them. They play essential roles just like proteinogenic or essential amino acids, and cells may not be able to synthesize them in large enough amounts to satisfy the body’s requirements — particularly during certain times (like during rapid growth, when healing from an injury, etc.) or if you live an active lifestyle. To augment the quantity your cells can produce, you must consume amino acids — like beta-alanine — in your diet or take them as supplements.

What Amino Acids Do for the Body

When you consume whole protein, whether it’s in a shake, in solid foods, or from supplements, the body’s digestive system breaks it down into amino acids. These amino acids then link together in the body, where they serve many important roles.

Some amino acids — like leucine and methionine — help with your body’s muscle and tissue growth. Others, like lysine and valine, are involved in producing energy, while isoleucine helps your body regulate energy. And others help with digestion, the production of hormones, mood regulation, brain function, and immune function.

CarnoSyn® beta-alanine is one amino acid that, when ingested, increases pH buffering capacity, delays fatigue, and improves focus and cognitive function. In fact, over 55 clinical studies support the athletic performance benefits of CarnoSyn®. It’s for these reasons that amino acid supplements like CarnoSyn® beta-alanine have become an integral part of serious athletes’ workout regimens. The International Society of Sport Nutrition (ISSN) supports such supplementation, and in 2022, officially recommended beta-alanine for tactical athletes, military, and first responders to achieve health and performance benefits.

Person in a kitchen holding a bottle | Carnosyn Health and Fitness Amino

Amino Acids — Safe for Supplementation?

When used by manufacturers appropriately, amino acid supplements like beta-alanine are safe for consumption. However, it’s important to know the source and quality of the ingredients found in your supplements. In the case of beta-alanine, only CarnoSyn® is globally patented and meets the industry’s most rigorous standards of quality. Generic impostors abound, and their inferior ingredients may lack consistency in quality, potency, and purity. To determine if the supplement you’re taking is safe, ask:

  • Is this product patented?
  • Is it guaranteed to be banned-substance free?
  • Is it made by a brand that is backed by proven scientific results?

Additionally, when supplementing, it’s best to take only the recommended dosage. The amount you should consume will vary depending on your performance goals. To see the benefits of beta-alanine, load at least 90 grams of beta-alanine over a period of 28 days, for an average of 3.2 grams per day. For maximum benefits, increase this amount to 179 grams over 28 days (an average of 6.4 grams per day).

If you’re looking to build muscle, enhance your capacity to exercise, and improve recovery, CarnoSyn® beta-alanine is a leading ingredient that can get you there — quickly and safely. Learn more about our CarnoSyn®-verified partners and how their products can help you meet your health and fitness goals.

TWO WAYS TO GET RESULTS

CarnoSyn® beta-alanine is available in two different forms—instant release and sustained release—offering two ways to dose. SR CarnoSyn® offers the same benefits as instant release CarnoSyn®, but in an advanced delivery system that allows for increased dosing for better results. When used in tandem, the combination of instant release and sustained release gives athletes the ability to stack their dosing for higher quantities of beta-alanine and even more performance gains.

CarnoSyn Beta-Alanine Logo

Instant Release

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Sustained Release

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]]> https://www.carnosyn.com/is-beta-alanine-an-amino-acid-supplement/feed/ 0 The Truth About The Top 5 Workout Myths https://www.carnosyn.com/the-truth-about-the-top-5-workout-myths/ https://www.carnosyn.com/the-truth-about-the-top-5-workout-myths/#respond Thu, 02 Feb 2023 19:39:45 +0000 https://www.carnosyn.com/?p=7532 It can be difficult to find the time to exercise regularly. Building a training routine that suits both your schedule and your health goals is even more of a challenge. From healthcare professionals to ‘fitfluencers’, workout trends, and fitness fads, there is a tremendous amount of information out there. Determining what’s true or false isn’t […]

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]]> It can be difficult to find the time to exercise regularly. Building a training routine that suits both your schedule and your health goals is even more of a challenge. From healthcare professionals to ‘fitfluencers’, workout trends, and fitness fads, there is a tremendous amount of information out there. Determining what’s true or false isn’t always clear. From a scientific research perspective, here’s the truth about the top 5 workout myths.

Myth #1: Strength training is only for bodybuilders.

False. Strength training, otherwise known as resistance training, is ideal for everyone across all age populations and athletic abilities. Through cross training, or engaging a variety of muscle groups, you can actually improve overall athletic performance. Strength training has a positive impact on the bones, connective tissue, and muscles and can even help prevent injury or the severity of injuries.

Myth #2: Weights will make you bulky.

False. You can absolutely lift weights without getting bulky. Yet, this is a very commonly believed myth regarding weight training, especially among women. Bodybuilders train for very long periods of time, maintain an intentionally high protein intake, and follow specific hypertrophy training programs to build significant muscle mass. For those looking to decrease fat body mass and increase lean muscle mass, weightlifting is an extremely productive way to achieve those goals.

Myth #3: Cardio is best for losing weight.

False. You actually lose more with weight training than cardio. Both cardio and weightlifting are effective for weight loss. However, only weight training causes the body to continue to burn calories well after your workout. This happens because weightlifting causes the tissues in the muscles to become more metabolically active–even while at rest.

Myth #4:  You don’t need supplements if you eat right.

False. Due to a variety of factors, you simply can’t get enough nutrition from diet alone. Foods rich in vitamins and minerals do not necessarily contain all the body needs to maintain optimal levels. For example, supplementing with beta-alanine provides significant health benefits like muscle recovery[1] and improved cognitive functioning[2]. When it comes to improving athletic performance, the beta-alanine from the body’s natural production and most diets is also not enough. Years of scientific studies show that taking at least 90 grams of beta-alanine over a 28-day period increases the working capacity of muscles[3] to help you build more muscle, faster[4]. That means taking an average of 3.2 grams per day, at a minimum, to get all the benefits. By taking beta-alanine daily–not just on workout days–you can maintain optimal levels of muscle carnosine.

Myth #5: All supplements are the same.

False. Not all supplements undergo the same safety and quality requirements. There is no shortage of cheap, generic beta-alanine on the market, however, CarnoSyn® is the only patented beta-alanine backed by the science of over 55 clinical studies. Many years and millions of dollars have been invested in scientific research and stringent quality control, leading CarnoSyn® to become the only beta-alanine that has successfully obtained New Dietary Ingredient (NDI) status with the FDA and self-affirmed Generally Recognized as Safe (GRAS). Not all beta-alanine supplements are the same. Only CarnoSyn® provides the reassurance that the beta-alanine is safe and effective.

It’s time to leave the latest fitness fads and trendy workout myths behind. Shape your training routine around what’s clinically proven to be ideal for your health. To avoid the myths and find the fuel you need to support your workouts, look for the CarnoSyn® logo on the label when shopping for your pre- or post-workout supplement label. Here is quick access to the products that contain the beta-alanine you can trust: CarnoSyn® Verified partners.

[1] Derave W, et al., 2007. Beta-alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters. J Appl Physiol., 103: 1736-1743.
[2] Furst T, Massaro A, Miller C, Williams BT, LaMacchia ZM, Horvath PJ. J Int Soc Sports Nutr. 2018 Jul 11;15(1):32. doi: 10.1186/s12970-018-0238-7. PMID: 29996843.
[3] Stout JR, et al., 2006. Effects of twenty-eight days of beta-alanine and creatine monohydrate supplementation on the physical working capacity at the neuromuscular fatigue threshold. J Strngth & Cond. Rsrch, 20(4): 928-931.
[4] Hoffman J, et al., 2006. Effect of creatine and beta-alanine supplementation on performance and endocrine responses in strength/power athletes. Int J Sport Nutr & Exer Metab., 16: 430-446.

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]]> https://www.carnosyn.com/the-truth-about-the-top-5-workout-myths/feed/ 0 The Best Time to Take Beta-Alanine https://www.carnosyn.com/the-best-time-to-take-beta-alanine/ https://www.carnosyn.com/the-best-time-to-take-beta-alanine/#comments Thu, 19 Jan 2023 22:34:56 +0000 https://www.carnosyn.com/?p=7520 Athletes know that beta-alanine is the go-to fuel to maximize their workouts. Greater focus, better performance, sustained endurance, and better gains are just a few of the benefits of beta-alanine. The question is–what can athletes do to fully harness beta-alanine? The answer–it’s all about the right dose at the right time. To get maximum benefits, […]

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]]> Athletes know that beta-alanine is the go-to fuel to maximize their workouts. Greater focus, better performance, sustained endurance, and better gains are just a few of the benefits of beta-alanine. The question is–what can athletes do to fully harness beta-alanine? The answer–it’s all about the right dose at the right time. To get maximum benefits, athletes should know the best time to take beta-alanine.

When is the Best Time to Take Beta-Alanine?

Consistency is key when it comes to the best time to take beta-alanine. Whether it’s cardio or leg day, or even time for recovery, beta-alanine should be taken at the same time every single day. There are a couple of reasons for this. The first has to do with how beta-alanine supplementation works. Beta-alanine combines with the amino acid histidine to form another amino acid called carnosine. Over time, carnosine buffers the pH decline that causes the onset of muscle fatigue and failure, while building endurance and improving recovery. This pH buffering helps delay and can even prevent muscular fatigue. That’s why it is important to take beta-alanine consistently. This ensures that the optimal levels of carnosine remain in the body. Bottom line: if you skip the gym, do not skip your beta-alanine.

Beta-alanine should be taken every day and at a minimum of 3.2g a day. The best time to take beta-alanine is normally 15 to 20 minutes before a workout. This helps athletes take advantage of the short-term effects beta-alanine has on the nervous system like increased mental focus. It also helps to give muscles a jumpstart on recovery. Some athletes choose to spread their intake out, dosing at regular intervals throughout the day. Other athletes select sustained release formulations of beta-alanine to maintain optimal levels throughout the day. This also helps to avoid the tingling sensation called paresthesia. Since beta-alanine is a stimulant and could keep you awake, it is not recommended before bed.

What is the Best Dose for Beta-Alanine?

As with any supplementation regimen, proper dosing is critical for optimizing physical performance. The best dose for beta-alanine is a minimum of 3.2 grams a day. Years of scientific studies show that taking at least 90 grams of beta-alanine over a 28-day period increases the working capacity of muscles to help you build more muscle, faster. That means taking a minimum of 3.2 grams per day to provide the body with the fuel needed to maintain optimal carnosine levels.

The recommended maximum daily dose of beta-alanine is 6.4 grams. Many athletes choose to support their intense workout routines by dosing at the highest levels. Most do what’s called stacking–supplementing with various formulations throughout the day. Studies prove that increasing beta-alanine intake to 179 grams over 28 days (an average of 6.4 grams per day) can significantly amplify muscle performance. This demonstrates that maximum dosing results in exponentially greater gains.

Three Ways to Get the Daily Dose of 3.2-6.4 Grams of Beta-Alanine

  1. Part of a pre-workout or post-workout
  2. A stand-alone product in a single dose or multiple doses
  3. A combination of pre/post formulations and stand-alone products

CarnoSyn Beta-alanine Banner

Beta-alanine has a loading period of 28 days. This is the amount of time required to experience all the benefits of beta-alanine supplementation.  After the loading period, beta-alanine should be taken every day to maintain the appropriate levels of carnosine in the body.

Not All Beta-Alanine is Created Equal.

CarnoSyn® is the only patented and certified beta-alanine on the market. Many years and millions of dollars have been invested in scientific research and stringent quality control, leading CarnoSyn® to become the only beta-alanine that has successfully obtained New Dietary Ingredient (NDI) status with the FDA and that has also achieved Generally Recognized as Safe (GRAS) self-affirmation. Containing ZERO banned substances, you’ll always know where your ingredients come from—and that they’re safe and effective —with CarnoSyn®.

Where Do I Find the Best Beta-Alanine?

To find the best beta-alanine, please visit the CarnoSyn® Verified page. Here you can browse the list of CarnoSyn®-Verified Brand Partners and find the beta-alanine products that provide the optimal dose at the best time. This list will also provide you with the sites and locations for purchasing CarnoSyn® directly.

 

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]]> https://www.carnosyn.com/the-best-time-to-take-beta-alanine/feed/ 1 How CarnoSyn® Works: Beta-Alanine’s Mechanism of Action in the Body https://www.carnosyn.com/how-carnosyn-works-beta-alanines-mechanism-of-action-in-the-body/ https://www.carnosyn.com/how-carnosyn-works-beta-alanines-mechanism-of-action-in-the-body/#respond Thu, 05 Jan 2023 20:22:04 +0000 https://www.carnosyn.com/?p=7483 In physics, Newton’s third law of motion states that every action has an equal and opposite reaction — a principle of inertia and counterforce that could also be used to describe the positive effects of safe, high-quality supplements on whole body health. In health and wellness, there’s a term for this: “mechanism of action.” This […]

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In physics, Newton’s third law of motion states that every action has an equal and opposite reaction — a principle of inertia and counterforce that could also be used to describe the positive effects of safe, high-quality supplements on whole body health. In health and wellness, there’s a term for this: “mechanism of action.” This describes how a molecule, such as a supplement or other substance, produces a specific pharmacological effect in the body (which may include the blocking of receptors, enzymes, stimulating hormone production, etc.). This knowledge is important because monitoring how a molecule affects the body allows for safe, successful dosing of certain supplements. In CarnoSyn® beta-alanine, one of its primary mechanisms of action is its ability to enhance intracellular buffering capacity, which results in a greater tolerance for sustained anaerobic activity. This makes it an effective sports nutrition supplement, but CarnoSyn® isn’t just for athletes—it‘s also ideal for individuals looking to improve their overall wellness. Here’s a closer look at how CarnoSyn® beta-alanine works and its effects on the body.

Beta-Alanine, Histidine, and Carnosine

Beta-alanine is an amino acid that is produced naturally in the body. When CarnoSyn® beta-alanine is introduced into the body, it binds with the amino acid histidine in the brain, the muscles, and other organs with a peptide bond. The result is the dipeptide called carnosine. Since beta-alanine is the rate-limiting factor in carnosine synthesis, our bodies demand more as we get older. However, it’s difficult to get the required amount of beta-alanine through diet alone. Beta-alanine supplementation has been shown to increase carnosine levels in the body (by up to 80 percent). More carnosine means better performance—along with improved brain health, systemic protection, muscle function, bone health, and heart health.

Understanding pH Decline and Carnosine’s Buffering Action

As exercise intensity increases, the major end-products of glucose metabolism are increasingly lactate and hydrogen ions which are generated in equal amounts. However, it is the highly reactive hydrogen ions that are responsible for the fall in pH in exercising muscle (a process also referred to as acidification). Throughout exercise, hydrogen ions can be actively transported out of the muscle cells and into circulation. However, the rate at which this can occur is limited, and, at higher exercise intensities, is insufficient in matching the increased rate of hydrogen ion production, resulting in progressive acidification. To the athlete, this manifests as the onset of fatigue/loss of muscle power. However, carnosine is able to buffer pH decline with its special chemical structure and property, the imidazole ring. This buffering action reduces the build-up of acidity that contributes to muscle fatigue and failure, while increasing endurance and improving recovery when training. For non-athletes, this buffering action is also crucial because the blood’s pH must remain constant (and not too acidic or too basic)—otherwise, the body’s enzymes and proteins will be unable to function.

Carnosine can Maintain proton buffering capacity, regulate calcium release and sensitivity, and provide protection against reactive oxygen species.

Beta-Alanine’s Effects on Overall Wellness

SR CarnoSyn® offers the same benefits as instant release CarnoSyn® but in an advanced delivery system that allows for increased dosing for faster results. Its sustained release formula increases carnosine levels in the body to promote everyday wellness and healthy aging. SR CarnoSyn® is patented and scientifically proven to improve brain health, systemic protection, muscle function, bone health, and heart health. Of significant value are carnosine’s antioxidant properties, which protect entire systems in the body from lipid peroxidation. During this process, oxidants such as free radicals attack lipids in cell membranes, which can result in membrane rupture and cell death. Whether oxidative damage is caused by aging or strenuous physical activity, increased carnosine levels help cells to fight these effects. The list of benefits goes on:

Brain and Mood Support

Carnosine acts as an anti-glycation agent in cells, which supports brain health and cognitive function. It is a powerful antioxidant, with studies showing carnosine helps improve attention, concentration, and task focus in adults. Increasing carnosine levels also promotes a healthy response to everyday stress and has been shown to slow down aging.

Immune Support and Systemic Health

Carnosine provides multi-system support for the essential structure and function of healthy immunity. It chelates heavy metals, supports healthy blood sugar levels, and helps the body’s cells fight oxidative damage. Carnosine is a provider of extracellular histidine and histamine, both needed for several physiological functions.

Muscle Function and Bone Health

Increasing carnosine levels improves muscle working capacity and muscle contraction, supporting the body as it undergoes age-related changes. In addition to the pH buffering function mentioned earlier, carnosine is also a regulator of calcium release and calcium sensitivity, which are both important for muscle contraction and provide powerful support for bone integrity in older adults.

Heart Health

In addition to protecting against lipid peroxidation in the body, carnosine helps to maintain proton buffering capacity, supports circulation and already-healthy blood pressure levels, and regulates muscle contractions. Whether you’re a fitness enthusiast looking to improve performance and speed up recovery or a non-athlete hoping to support healthy aging and overall wellness, CarnoSyn® and SR CarnoSyn® are the only beta-alanine supplements to be clinically proven in over 55 clinical studies to be safe and effective.

CarnoSyn® Beta-Alanine: Two Forms, Two Ways to Dose

CarnoSyn® is an instant release beta-alanine that helps athletes of all abilities to reach peak performance, while SR CarnoSyn® is a sustained release form of beta-alanine that delivers higher dosing levels of beta-alanine over time and offers multi-system support for everyday wellness and healthy aging. Whatever your health or fitness goals, CarnoSyn® is the only beta-alanine that is patented, versatile, safe, and backed by science. Learn more about the benefits of instant-release CarnoSyn® and SR CarnoSyn® to determine which form of beta-alanine is right for you.

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